Office of Cancer Complimentary and Alternative Medicine
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Updated: 05/09/13

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Fatigue and CAM
person lying on bed

Cancer-related fatigue is the most common side effect for cancer patients undergoing treatment of any kind, and can linger well past treatment’s end. It has been reported by 14-96% of cancer patients. Cancer-related fatigue differs from other types of fatigue because it is not completely relieved by rest or sleep and can interfere with daily functioning and quality of life. While some pharmacologic treatments have been used for treatment, such as psychostimulants, other nonpharmacologic interventions such as physical activity, psychosocial interventions, and others are also suggested to help alleviate fatigue. The reasons fatigue persists in cancer patients is not well understood, especially in the absence of contributing factors such as anemia, nutritional deficiencies, and mood disorders, along with the cancer treatment itself. Below is an collection of some sources pertaining to cancer-related fatigue and complementary and alternative medicine.

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Research Highlights on Fatigue and CAM

Clinical Trials

Resources from around NIH

Selection NIH-supported scientific literature (PubMed®):

Additional Resources