Bioelectricity and Cancer Conference

Overview

Bioelectricity refers to the electrical properties and signaling within living cells and tissues. It plays a crucial role in various biological processes, including embryonic development, wound healing, tissue regeneration and cancer. Alterations in the cellular voltage membrane potential (Vmem) disrupt cellular signaling pathways during cancer initiation, promotion, and progression. Ion channels (e.g., voltage-gated cation channels, mechanosensitive channels) responsible for Vmem are often abnormal in malignant cells and can activate aberrant signaling pathways. Detection of altered Vmem in tissues maybe useful in assessing malignant potential and modifications of Vmem in malignant cells have been shown in preclinical studies to induce functional changes back toward the non-malignant phenotype. The conference will present and discuss recent research findings relevant to the role of bioelectricity in normal physiology, cancer biology, diagnosis, and management.

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